中文
Ethnobotany of China

KINGDOM: || PHYLUM: || CLASS: || ORDER: || FAMILY:伞形科 UMBELLIFERAE || GENUS:

川芎 Ligusticum chuanxiong

Accepted name Conioselinum anthriscoides 'Chuanxiong' (Apiaceae) WCVP · synonym, resolved to accepted name
Catalogue of Life China 金芎 (differs from the Chinese name in this database)
Flora treatments

《中国植物志》|| 伞形科 UMBELLIFERAE ||藁本属 Ligusticum L. ||川芎 Ligusticum chuanxiong S. H. Qiu, Y. Q. Zeng, K. Y. Pan, Y. C. Tang & J.M. Xu

5. 川芎(本草纲目)芎䓖(神农本草经) 图版99: 6-8
Ligusticum chuanxiong Hort. 邱淑华等, 植物分类学报17 (2): 101. 1979; 内蒙古植物志4: 182. 84. 1979. ——Ligusticum wallichii auct. non Franch.: 中药志1: 67. 图44. 1959.
多年生草本,高40-60厘米。根茎发达,形成不规则的结节状拳形团块,具浓烈香气。茎直立,圆柱形,具纵条纹,上部多分枝,下部茎节膨大呈盘状 (苓子)。茎下部叶具柄,柄长3-10厘米,基部扩大成鞘;叶片轮廓卵状三角形,长12-15厘米,宽10-15厘米,3-4回三出式羽状全裂,羽片4-5对,卵状披针形,长6-7厘米,宽5-6厘米,末回裂片线状披针形至长卵形,长2-5毫米,宽1-2毫米,具小尖头;茎上部叶渐简化。复伞形花序顶生或侧生;总苞片3-6,线形,长0.5-2.5厘米;伞辐7-24,不等长,长2-4厘米,内侧粗糙;小总苞片4-8,线形,长3-5毫米,粗糙;萼齿不发育;花瓣白色,倒卵形至心形,长1.5-2毫米,先端具内折小尖头;花柱基圆锥状,花柱2,长2-3毫米,向下反曲。幼果两侧扁压,长2-3毫米,宽约1毫米;背棱槽内油管1-5,侧棱槽内油管2-3,合生面油管6-8。花期7-8月,幼果期9-10月。
栽培植物,主产四川(灌县),在云南、贵州、广西、湖北、江西、浙江、江苏、陕西、甘肃、内蒙古、河北等省区均有栽培。模式标本采自灌县。
根茎供药用,功能行气开郁,祛风燥湿,活血止痛,治头痛旋晕、肋痛腹疼、经闭、难产、痈疽疮疡等症。
四川另产茶芎,又名大叶川芎,因长期营养繁殖,未见花果,其分类位置尚难确定,有待深入研究。


Source 中国植物物种信息数据库


Plant use records
Chinese name Vernacular name Plant Ethnic group Use Source
川芎 川芎 川芎 Ligusticum chuanxiong Hort. Medicinal 中华本草


Historical formulas containing this species
Use in historical formulas by period (12362 formulas in total)
Use in historical formulas by periodPre-Qin: 0Pre-QinHan: 3434HanWei–Jin & N–S: 8383Wei–Jin& N–SSui–Tang & Five Dynasties: 827827Sui–Tang& Five DynastiesSong: 46344634SongJin–Yuan: 562562Jin–YuanMing: 38243824MingQing: 23982398Qing




Wild economic plants of the Qinghai–Tibet Plateau (field survey)
Plant name Local name Family Life form Part used Folk use Voucher Locality Ethnic group Region
Ligusticum chuanxiong Hort ma-tsa-la/a-la-kho-sris-rtong Apiaceae Herb 种子,嫩叶 嫩叶被用作调料,种子被用作调料或治疗牙痛 CT005 Chentang (Dinggyê) Sherpa Core Himalaya
Ligusticum chuanxiong Hort Apiaceae Herb 种子,嫩叶 食用:蔬菜,保健品 ;腰疼 LZY-LJG21 Lijiang Naxi Eastern Himalaya

Research papers
Title Authors Journal Date
Ligusticum chuanxiong and Its Decoctions: Effects and Underlying Mechanisms of Action on Stroke Yang, Cindy L. H.; Or, Terry C. T.; Lau, Jonathan S. H.; Lau, Allan S. Y. RECENT TRENDS IN MEDICINAL PLANTS RESEARCH 2012
Comparative analysis of Ligusticum chuanxiong and related umbelliferous medicinal plants by high performance liquid chromatography-electrospray ionization mass spectrometry Yi, Tao; Leung, Kelvin Sze-Yin; Lu, Guang-Hua; Zhang, Hao PLANTA MEDICA
GC-MS fingerprints for discrimination of Ligusticum chuanxiong from Angelica Yang, Baijuan; Chen, Junhui; Lee, Frank Sen-Chun; Wang, Xiaoru JOURNAL OF SEPARATION SCIENCE OCT 2008
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice Yang, Wen-Jing; Li, Yan-Ru; Gao, Hui; Wu, Xue-Yi; Wang, Xiao-Ling; Wang, Xiao-Ning; Xiang, Lan; Ren, Dong-Mei; Lou, Hong-Xiang; Shen, Tao JOURNAL OF ETHNOPHARMACOLOGY JUN 26 2012
Du-Huo-Ji-Sheng-Tang and its active component Ligusticum chuanxiong promote osteogenic differentiation and decrease the aging process of human mesenchymal stem cells Wang, Jir-You; Chen, Wei-Ming; Wen, Che-Sheng; Hung, Shih-Chieh; Chen, Pei-Wen; Chiu, Jen-Hwey JOURNAL OF ETHNOPHARMACOLOGY OCT 28 2010
Danhong Huayu Koufuye prevents venous thrombosis through antiinflammation via Sirtuin 1/NF-kappa B signaling pathway Liu, Han; Li, Peng; Lin, Juan; Chen, Wenpei; Guo, Haibiao; Lin, Jianyun; Liu, Jin; Lu, Ziqi; Yao, Xiaolan; Chen, Yang; Lin, Baoqin JOURNAL OF ETHNOPHARMACOLOGY APR 24 2021
Neuroprotective effect of Da Chuanxiong Formula against cognitive and motor deficits in a rat controlled cortical impact model of traumatic brain injury Liu, Zhi-Ke; Ng, Chun-Fai; Shiu, Hoi-Ting; Wong, Hing-Lok; Chin, Wai-Ching; Zhang, Jin-Fang; Lam, Ping-Kuen; Poon, Wai-Sang; Lau, Clara Bik-San; Leung, Ping-Chung; Ko, Chun-Hay JOURNAL OF ETHNOPHARMACOLOGY SEP 15 2019
Traditional Chinese patent medicine Zhixiong Capsule (ZXC) alleviated formed atherosclerotic plaque in rat thoracic artery and the mechanism investigation including blood-dissolved-component-based network pharmacology analysis and biochemical validation Zhai, Jianxiu; Ren, Zhaohui; Wang, Yuwei; Han, Mingshu; Han, Na; Liu, Zhihui; Li, Sikai; Yin, Jun JOURNAL OF ETHNOPHARMACOLOGY
The antithrombotic effect of RSNK in blood-stasis model rats Dang, Xuan; Miao, Jing-jing; Chen, An-qi; Li, Peng; Chen, Lin; Liang, Jin-ru; Xie, Ren-ming; Zhao, Ye JOURNAL OF ETHNOPHARMACOLOGY SEP 15 2015
The effect of ligustrazine on L-type calcium current, calcium transient and contractility in rabbit ventricular myocytes Ren, Zhiqiang; Ma, Jihua; Zhang, Peihua; Luo, Antao; Zhang, Shuo; Kong, Linghao; Qian, Chunping JOURNAL OF ETHNOPHARMACOLOGY DEC 18 2012
Ligusticum chuanxiong exerts neuroprotection by promoting adult neurogenesis and inhibiting inflammation in the hippocampus of ME cerebral ischemia rats Wang, Min; Yao, Mingjiang; Liu, Jianxun; Takagi, Norio; Yang, Bin; Zhang, Miao; Xu, Li; Ren, Junguo; Fan, Xiaodi; Tian, Fangze JOURNAL OF ETHNOPHARMACOLOGY
Pharmacokinetic comparative study of gastrodin after oral administration of Gastrodia elata Bl. extract and its compatibility with the different indigents of Ligusticum chuanxiong Hort. to rats Hu, Peng-yi; Yue, Peng-fei; Zheng, Qin; Yang, Ming; Zhang, Guo-song; Wu, Bin; Liu, Dan JOURNAL OF ETHNOPHARMACOLOGY SEP 15 2016
The evaluation of embryotoxicity of Ligusticum chuanxiong on mice and embryonic stem cells Wang, Hongyang; Bao, Qian; Yi, Hua; Xia, Quan JOURNAL OF ETHNOPHARMACOLOGY JUL 15 2019
Impact of the Chinese herbal medicines on dual antiplatelet therapy with clopidogrel and aspirin: Pharmacokinetics and pharmacodynamics outcomes and related mechanisms in rats Xiao, Min; Qian, Chenyu; Luo, Xi; Yang, Mengbi; Zhang, Yufeng; Wu, Cheyuen; Mok, Chungtong; Lee, Puiwai; Zuo, Zhong JOURNAL OF ETHNOPHARMACOLOGY MAY 10 2019
Ligusticum chuanxiong as a potential neuroprotectant for preventing serum deprivation-induced apoptosis in rat pheochromocytoma cells: Functional roles of mitogen-activated protein kinases Lin, Yun-Lian; Wang, Guei-Jane; Huang, Chuen-Lin; Lee, Yi-Chao; Liao, Wei-Chen; Lai, Wen-Lin; Lin, Yen-Ju; Huang, Nai-Kuei JOURNAL OF ETHNOPHARMACOLOGY APR 21 2009
Pharmacokinetics, tissue distribution and metabolism of senkyunolide I, a major bioactive component in Ligusticum chuanxiong Hort. (Umbelliferae) He, Chun-Yong; Wang, Shuo; Feng, Yi; Liang, Shuang; Lin, Xiao; Xu, De-Sheng; Ruan, Ke-Feng JOURNAL OF ETHNOPHARMACOLOGY AUG 1 2012
In vivo metabolites and plasma exposure of TongMai Keli analyzed by UHPLC/DAD/qTOF-MS and LC/MS/MS Liu, Chun-fang; Qiao, Xue; Liu, Ke-di; Miao, Wen-juan; Li, Yan-jiao; Liu, Yang; Jiang, Yan-yan; Bo, Tao; Shi, Ren-bing; Guo, De-an; Ye, Min JOURNAL OF ETHNOPHARMACOLOGY JAN 30 2013
Synergistic interaction between the Ligusticum chuanxiong constituent butylidenephthalide and the nitric oxide donor sodium nitroprusside in relaxing rat isolated aorta Chan, Sunny Sun-Kin; Jones, Robert Leslie; Lin, Ge JOURNAL OF ETHNOPHARMACOLOGY MAR 18 2009
Hyphenated chromatography detection and compound-target-disease investigation on herb-pair Chuanxiong Rhizoma - Xiangfu Rhizoma Zhou, Yu; Yan, Pan; He, Min; Hong, Liang; Cao, Qing JOURNAL OF ETHNOPHARMACOLOGY OCT 28 2019
Efficacy and safety of Xuebijing injection (a Chinese patent) for sepsis: A meta-analysis of randomized controlled trials Li, Chengyu; Wang, Ping; Zhang, Li; Li, Min; Lei, Xiang; Liu, Si; Feng, Zhiqiao; Yao, Yongming; Chang, Bai; Liu, Baoshan; Shang, Hongcai JOURNAL OF ETHNOPHARMACOLOGY OCT 5 2018
Pharmacokinetics, brain distribution, release and blood-brain barrier transport of Shunaoxin pills Wu, Kai; Wang, Zhan-Zhang; Liu, Dan; Qi, Xian-Rong JOURNAL OF ETHNOPHARMACOLOGY FEB 12 2014
A traditional Chinese formula composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma (Da Chuanxiong Formula) suppresses inflammatory response in LPS -induced RAW 264.7 cells through inhibition of NF-kappa B pathway Liu, Zhi-Ke; Ng, Chun-Fai; Shiu, Hoi-Ting; Wong, Hing-Lok; Wong, Chun-Wai; Li, Kai-Kai; Zhang, Jin-Fang; Lam, Ping-Kuen; Poon, Wai-Sang; Lau, Clara Bik-San; Leung, Ping-Chung; Ko, Chun-Hay JOURNAL OF ETHNOPHARMACOLOGY JAN 20 2017
The effects of Chuanxiong on the pharmacokinetics of warfarin in rats after biliary drainage Li, Haigang; Zhang, Chunhu; Fan, Rong; Sun, Hua; Xie, Haitang; Luo, Jiekun; Wang, Yang; Lv, Huiying; Tang, Tao JOURNAL OF ETHNOPHARMACOLOGY DEC 4 2016
Analysis of the chemical composition, acute toxicity and skin sensitivity of essential oil from rhizomes of Ligusticum chuanxiong Zhang, Hong; Han, Ting; Yu, Cheng-Hao; Jiang, Yi-Ping; Peng, Cheng; Ran, Xia; Qin, Lu-Ping JOURNAL OF ETHNOPHARMACOLOGY DEC 18 2012
Pharmacokinetics comparative study of a novel Chinese traditional herbal formula and its compatibility Zheng, Qin; Yue, Peng-Fei; Wu, Bin; Hu, Peng-Yi; Wu, Zhen-Feng; Yang, Ming JOURNAL OF ETHNOPHARMACOLOGY SEP 1 2011
In vitro anti-Helicobacter pylori action of 30 Chinese herbel medicines used to treat ulcer diseases Li, Y; Xu, C; Zhang, QA; Liu, JY; Tan, RX JOURNAL OF ETHNOPHARMACOLOGY APR 26 2005
The current evidence for the treatment of sepsis with Xuebijing injection: Bioactive constituents, findings of clinical studies and potential mechanisms Li, Chengyu; Wang, Ping; Li, Min; Zheng, Rui; Chen, Shiqi; Liu, Si; Feng, Zhiqiao; Yao, Yongming; Shang, Hongcai JOURNAL OF ETHNOPHARMACOLOGY JAN 30 2021
EFFECT OF SLIMAX, A CHINESE HERBAL MIXTURE, ON OBESITY WIJAYA, E; WU, ZM; NG, F INTERNATIONAL JOURNAL OF PHARMACOGNOSY MAR 1995
A systematic review on the rhizome of Ligusticum chuanxiong Hort. (Chuanxiong) Chen, Zhejie; Zhang, Chen; Gao, Fei; Fu, Qiang; Fu, Chaomei; He, Yao; Zhang, Jinming FOOD AND CHEMICAL TOXICOLOGY SEP 2018
Cadmium and lead mixtures are less toxic to the Chinese medicinal plant Ligusticum chuanxiong Hort. Than either metal alone Zeng, Jian; Li, Xiaoyuan; Wang, Xiangxiang; Zhang, Kehao; Wang, Yi; Kang, Houyang; Chen, Guangdeng; Lan, Ting; Zhang, Zhongwei; Yuan, Shu; Wang, Changquan; Zhou, Yonghong ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY APR 15 2020
The Role of Traditional Chinese Herbal Medicines and Bioactive Ingredients on Ion Channels: A Brief Review and Prospect Huang, Yian; Ma, Shumei; Wang, Yan; Yan, Renjie; Wang, Sheng; Liu, Nan; Chen, Ben; Chen, Jia; Liu, Li CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS 2019
Identification and comparative determination of senkyunolide A in traditional Chinese medicinal plants Ligusticum chuanxiong and Angelica sinensis by HPLC coupled with DAD and ESI-MS Yi, T; Leung, KSY; Lu, GH; Zhang, H; Chan, K CHEMICAL & PHARMACEUTICAL BULLETIN NOV 2005
High tetramethylpyrazine production by the endophytic bacterial Bacillus subtilis isolated from the traditional medicinal plant Ligusticum chuanxiong Hort. Yin, D. D.; Yang, M.; Wang, Y. L.; Yin, D. K.; Liu, H. K.; Zhou, M.; Li, W.; Chen, R.; Jiang, S. S.; Ou, M. F.; Xu, F. AMB EXPRESS
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