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A new phenolic compound with antioxidant activity from the branches and leaves of Pyrus pashia

Authors Li, Zhen-Jie; Zheng, Xi; Wan, Chun-Ping; Cai, Le; Li, Ying; Huang, Lin; Ding, Zhong-Tao

Journal NATURAL PRODUCT RESEARCH , MAY 18 2016,10:30

DOI 10.1080/14786419.2015.1046130 PubMed 26119567

Abstract The branches and leaves of Pyrus pashia are used to cure abdominal pain and diarrhoea in Chinese folk medicine. A new phenilic compound, 4-O--d-glucopyranosylbenzyl-benzoate ester (1), along with 21 known ones (2-22) were isolated from the branches and leaves of this plant. Compounds 2 and 3 displayed remarkable antioxidant activities against 1,1-diphenyl-2-picrylhydrazyl radical (IC50=13.26 +/- 0.04M, 13.28 +/- 0.11M, respectively), which were at the same grade as positive control rutin. The caffeoyl group in compounds 2 and 3 was supposed to play an important role in the antioxidant activities.

Species covered 川梨(原变种) Pyrus pashia