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[Studies on the active constituents of the Chinese traditional medicine Polygonatum odoratum (Mill.) Druce].

作者 Lin, H W; Han, G Y; Liao, S X

期刊 Yao xue xue bao = Acta pharmaceutica Sinica , 1994,3:29

PubMed 8079648

摘要 From the ethanol extract of the Chinese traditional medicine, rhizomes of Polygonatum odoratum, a new steroidal saponin POD-II together with beta-sitosterol and its glucoside, and three known saponins were isolated. On the basis of chemical evidence and spectral analysis (UV, IR, EI-MS, 1HNMR and 13CNMR), the structure of POD-II was elucidated as 3-O-beta-D-glucopyranosyl-(1-->2)-[beta-D-xylopyranosyl-(1-->3)]-beta-D- glucopyranosyl-(1-->4)-galactopyranosyl-25(R)-spirost-5-en-3 beta,14 alpha-diol. Preliminary pharmacological tests showed that POD-II could induce the colony stimulating factor (CSF) in mouse serum; and POD-III, at the concentration of 0.1 microgram.ml-1 was shown to synergize the suboptimal and optimal concentration of Con A and lipopolysaccharide to stimulate lymphocytes proliferation.

涉及物种 玉竹 Polygonatum odoratum