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Ethnobotany, Phytochemistry and Pharmacological Properties of Eucommia ulmoides: A Review

作者 Wang, Chao-Yong; Tang, Li; He, Jian-Wu; Li, Jing; Wang, Yuan-Zhong

期刊 AMERICAN JOURNAL OF CHINESE MEDICINE , 2019,2:47

DOI 10.1142/S0192415X19500137 PubMed 30857406

摘要 Eucommia ulmoides Oliver, a single species of Eucommia genus belonging to the Eucommiaceae family, is an endemic in China and has been used in traditional Chinese medicine for nearly two thousand years. Records from different historical periods highlight E. ulmoides and its officinal botanical parts, usefulness in adaptation to disease and its central role in Chinese medicine theory. There are also historical collection documents for minorities in China. Tearing the leaves, bark and fruit produces strands of latex; a description of E. ulmoides''s morphological features is recorded in this paper. This review summarizes 204 natural compounds isolated from this plant, which are divided into seven categories: lignans, iridoids, flavonoids, phenols, steroids, terpenes and others. These components possess wide-ranging pharmacological efficacies, such as antihypertensive, antihyperglycemic, antihyperlipidemia, anti-oxidative, anti-osteoporosis, antitumor, immunomodulatory and neuroprotective activities. This review aims to provide a reference for extensive researches of E. ulmoides crude drugs, especially for quality control, biosynthesis and structure modification of active ingredients and pharmacological mechanism.

涉及物种 杜仲 Eucommia ulmoides