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Demonstration of the myocardial salvage effect of lithospermic acid B isolated from the aqueous extract of Salvia miltiorrhiza.

作者 Fung, K P; Zeng, L H; Wu, J; Wong, H N; Lee, C M; Hon, P M; Chang, H M; Wu, T W

期刊 Life sciences , 1993,22:52

DOI 10.1016/0024-3205(93)90471-E PubMed 8492636

摘要 Lithospermic acid B has been isolated to > 95% purity by high performance liquid chromatography from the aqueous extract of the roots of Salvia miltiorrhiza. When infused at 5.5 mumoles/kg into the post-ischemic rabbit heart, it reduced by 62 +/- 10% (n = 8) the myocardial damage found in the saline control in a rabbit ischemia-reperfusion model.

涉及物种 丹参 Salvia miltiorrhiza