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[Antidepressant effect of ethanol extracts from three species of sect. Hypericum medicinal plants in mice].

Authors Wan, Deguan; Pei, Jin; Zhou, Mingmei; Wang, Guangzhi

Journal Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials , 2003-Mar,3:26

PubMed 12856470

Abstract OBJECTIVE: To explore the antidepressant actions of ethanol extracts from three species of sect. Hypericum medicinal plants.METHODS: The forced swimming test and mouse tail suspensions in mice were used.RESULT: Ethanol extracts of sect. Hypericum medicinal plants significantly shortened motionless time of mice forced swimming and despair time of mouse tail suspension in the two behavior despair animal models of depression. The effect of H. faberi was weaker than that of H. perforatum.CONCLUSION: These findings demonstrated that the extracts from three species of sect. Hypericum medicinal plants possessed obvious antidepressant activity.

Species covered 金丝桃属 Hypericum