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Screening of anti-Helicobacter pylori herbs deriving from Taiwanese folk medicinal plants

Authors Wang, YC; Huang, TL

Journal FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY , FEB 1 2005,2:43

DOI 10.1016/j.femsim.2004.09.008 PubMed 15681161

Abstract In this study, extracts from 50 Taiwanese folk medicinal plants were examined and screened for anti-Helicobacter pylori activity. Ninety-five percent ethanol was used for herbal extraction. Paederia scandens (Lour.) Merr. (PSM), Plumbago zeylanica L. (PZL), Anisomeles indica (L.) O. Kuntze (AIOK), Bombax malabaricum DC. (BMDC) and Alpinia speciosa (J. C. Wendl.) K. Schum. (ASKS) and Bombax malabaricum DC. (BMDC) all demonstrated strong anti-H. pylori activities. The minimum inhibitory concentration values of the anti-H. pylori activity given by the five ethanol herb extracts ranged from 0.64 to 10.24 mg ml(-1). Twenty-six herbs, including Artemisia argui Levl. et Vant (AALEV), Phyla nodiflora (Linn.) Greene (PNG) and others, showed moderate antiH. pylori activity. The additional 19 herbs, including Areca catechu Linn. (ACL), Euphorbia hirta Linn. (EHL) and Gnaphalium adnatuni Wall. ex DC. (GAWEDC), possessed lower anti-H. pylori effects. About half of the Taiwanese folk medicinal plants tested, demonstrated to possess higher anti-H. pylori activity. (C) 2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.

Species covered 白花丹 Plumbago zeylanica 槟榔 Areca catechu 过江藤 Phyla nodiflora 月桃 Alpinia zerumbet 飞扬草 Euphorbia hirta 蒿属 Artemisia 鸡矢藤(原变种) Paederia scandens 木棉 Bombax malabaricum